Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus.

Authors :: Malebo HM
Jonker SA
Waibel R
Nkunya MH
Source :: Natural products and bioprospecting [Nat Prod Bioprospect] 2014 Apr; Vol. 4 (2), pp. 101-5. Date of Electronic Publication: 2014 Apr 02.
Publication Year :: 2014
Abstract: New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3'-hydroxy-3'-methyl-1'-acetyloxy-but-2'-yl)indole (1) alongside the known hexalobines 3-(2',3'-dihydroxy-3'-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans.