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[Treatment of pemphigus with plasmapheresis].
- Source :
-
Harefuah [Harefuah] 1989 Sep; Vol. 117 (5-6), pp. 135-7. - Publication Year :
- 1989
-
Abstract
- Therapeutic plasmapheresis was successfully used in a 29-year-old man with corticosteroid-resistant pemphigus vulgaris who had severe side-effects from the medication. 4 plasmaphereses were performed over a period of 3 weeks with removal of a total of 7900 ml of plasma. Concurrently he received large doses of adrenal steroids and Imuran. There was clinical improvement soon after the first plasmapheresis and 8 weeks after the treatment was started he was free of lesions. IC-Ab titers markedly decreased during the course of treatment and continued to decrease after it was completed. Side-effects were few and relatively mild. Plasmapheresis may be a useful adjunct in the treatment of pemphigus vulgaris resistant to conventional therapy. It may be used initially together with corticosteroids, giving more rapid improvement, as well as a corticosteroid-sparing effect.
Details
- Language :
- Hebrew
- ISSN :
- 0017-7768
- Volume :
- 117
- Issue :
- 5-6
- Database :
- MEDLINE
- Journal :
- Harefuah
- Publication Type :
- Academic Journal
- Accession number :
- 2485756