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CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains.

Authors :
Wright PR
Georg J
Mann M
Sorescu DA
Richter AS
Lott S
Kleinkauf R
Hess WR
Backofen R
Source :
Nucleic acids research [Nucleic Acids Res] 2014 Jul; Vol. 42 (Web Server issue), pp. W119-23. Date of Electronic Publication: 2014 May 16.
Publication Year :
2014

Abstract

CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the existing tool IntaRNA (Interacting RNAs) in order to predict targets, interaction domains and consequently the regulatory networks of bacterial small RNA molecules. The CopraRNA prediction results are accompanied by extensive postprocessing methods such as functional enrichment analysis and visualization of interacting regions. Here, we introduce the functionality of the CopraRNA and IntaRNA webservers and give detailed explanations on their postprocessing functionalities. Both tools are freely accessible at http://rna.informatik.uni-freiburg.de.<br /> (© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.)

Details

Language :
English
ISSN :
1362-4962
Volume :
42
Issue :
Web Server issue
Database :
MEDLINE
Journal :
Nucleic acids research
Publication Type :
Academic Journal
Accession number :
24838564
Full Text :
https://doi.org/10.1093/nar/gku359