Prevalence of Toxoplasma gondii and Toxocara canis among patients with uveitis.

Authors :: Lim SJ
Lee SE
Kim SH
Hong SH
You YS
Kwon OW
Kim HS
Source :: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2014 Oct; Vol. 22 (5), pp. 360-6. Date of Electronic Publication: 2014 May 15.
Publication Year :: 2014
Abstract: Purpose: To investigate the prevalence of Toxoplasma gondii and Toxocara canis in patients with uveitis.<br />Method: Patients with uveitis were examined. Serum antibodies to T. gondii and T. canis were tested by using enzyme-linked immunosorbent assay (ELISA). Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH).<br />Results: 98 patients were enrolled. Mean age was 43.5 ± 13.2 years. Six patients were seropositive for T. gondii with the following pattern-anterior uveitis: 1; posterior uveitis with retinitis: 2; pan uveitis: 2. One patient had a positive result of PCR for T.gondii in AH, who showed pan uveitis. 23 patients were positive to serum IgG for T. canis with the following clinical manifestation-granuloma: 6; pigmented scar: 3; virtrits: 6-but none were PCR positive.<br />Conclusion: T.gondii and T.canis are still one of the important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis even in adult.