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Health-related quality of life after myocardial infarction, does choice of method make a difference?
- Source :
-
Scandinavian cardiovascular journal : SCJ [Scand Cardiovasc J] 2014 Aug; Vol. 48 (4), pp. 216-22. Date of Electronic Publication: 2014 Jun 26. - Publication Year :
- 2014
-
Abstract
- Objectives: The aim of this study was to compare health-related quality of life (HRQoL) scores obtained from the instrument Short Form (SF)-36 through the so-called SF-6D utilities, and those obtained from 15D, in patients with ST-elevation myocardial infarction (STEMI), and to evaluate the consequences in estimation of quality adjusted life years (QALYs).<br />Design: This was a sub-study of the Norwegian District Treatment of STEMI, in which patients with STEMI treated with tenecteplase, were randomized to early angioplasty or standard management (n = 266). HRQoL data were collected at all visits (0, 1, 3, 7 and 12 months). All patients with complete data were included (n = 248).<br />Results: The score range was 0.33-1.0 for SF-6D and 0.49-1.0 for 15D. Mean utility scores from 15D were higher and had different distribution compared to scores from SF-6D. Mean QALY for the whole group was higher using 15D than SF-6D (0.89 vs. 0.77). The incremental number of QALYs with early angioplasty compared to standard treatment was 0.005 (95% CI: - 0.018 to 0.028) using SF-6D, and 0.004 (95% CI: - 0.010 to 0.018) using the 15D instrument.<br />Conclusions: Choice of instrument may influence HRQoL scores, but not necessarily the gain in QALYs.
- Subjects :
- Aged
Angioplasty
Female
Fibrinolytic Agents administration & dosage
Humans
Male
Middle Aged
Myocardial Infarction diagnosis
Myocardial Infarction therapy
Norway
Predictive Value of Tests
Prospective Studies
Tenecteplase
Thrombolytic Therapy
Time Factors
Time-to-Treatment
Tissue Plasminogen Activator administration & dosage
Treatment Outcome
Myocardial Infarction psychology
Quality of Life
Quality-Adjusted Life Years
Surveys and Questionnaires
Subjects
Details
- Language :
- English
- ISSN :
- 1651-2006
- Volume :
- 48
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Scandinavian cardiovascular journal : SCJ
- Publication Type :
- Academic Journal
- Accession number :
- 24828790
- Full Text :
- https://doi.org/10.3109/14017431.2014.923581