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Eosinophilic esophagitis: overview of clinical management.
- Source :
-
Gastroenterology clinics of North America [Gastroenterol Clin North Am] 2014 Jun; Vol. 43 (2), pp. 329-44. Date of Electronic Publication: 2014 Mar 21. - Publication Year :
- 2014
-
Abstract
- A validated disease-specific symptom-assessment tool for eosinophilic esophagitis (EoE) has yet to be approved by regulatory authorities for use in clinical trials. Relevant end points for daily practice include EoE-related symptoms and esophageal eosinophilic inflammation. Endoscopic features should also be taken into account when establishing a therapy plan. A reasonable clinical goal is to achieve a reduction in EoE-related symptoms and esophageal eosinophilic inflammation. Evidence is increasing to support an anti-inflammatory maintenance therapy, as this can reduce esophageal remodeling. In EoE patients in clinical remission, annual disease monitoring with symptom, endoscopic, and histologic assessments of sustained treatment response is recommended.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)
- Subjects :
- Algorithms
Humans
Eosinophilic Esophagitis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1558-1942
- Volume :
- 43
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Gastroenterology clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 24813519
- Full Text :
- https://doi.org/10.1016/j.gtc.2014.02.014