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Curcumin, a component of golden spice: from bedside to bench and back.

Authors :
Prasad S
Gupta SC
Tyagi AK
Aggarwal BB
Source :
Biotechnology advances [Biotechnol Adv] 2014 Nov 01; Vol. 32 (6), pp. 1053-64. Date of Electronic Publication: 2014 Apr 30.
Publication Year :
2014

Abstract

Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of years, it is only within the past century that we learned about the chemistry of its active component, curcumin. More than 6000 articles published within the past two decades have discussed the molecular basis for the antioxidant, anti-inflammatory, antibacterial, antiviral, antifungal, and anticancer activities assigned to this nutraceutical. Over sixty five clinical trials conducted on this molecules, have shed light on the role of curcumin in various chronic conditions, including autoimmune, cardiovascular, neurological, and psychological diseases, as well as diabetes and cancer. The current review provides an overview of the history, chemistry, analogs, and mechanism of action of curcumin.<br /> (Published by Elsevier Inc.)

Details

Language :
English
ISSN :
1873-1899
Volume :
32
Issue :
6
Database :
MEDLINE
Journal :
Biotechnology advances
Publication Type :
Academic Journal
Accession number :
24793420
Full Text :
https://doi.org/10.1016/j.biotechadv.2014.04.004