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Mixed tumors of the skin. A histological and immunohistochemical study.
- Source :
-
The American Journal of dermatopathology [Am J Dermatopathol] 1989 Oct; Vol. 11 (5), pp. 413-28. - Publication Year :
- 1989
-
Abstract
- Sixty-four specimens of mixed tumors of the skin were studied by conventional microscopy. Sections from all 64 specimens were stained by hematoxylin and eosin, and sections from 18 of those specimens were stained by immunoperoxidase techniques for the presence of S-100 protein, carcino-embryonic antigen (CEA), keratin, actin, vimentin, epithelial membrane antigen (EMA), and gross cystic disease fluid protein-15 (GCDFP-15). Two distinctive histopathological patterns of mixed tumors of the skin became apparent, namely, apocrine and eccrine. Mixed tumors with apocrine features are by far the most common. Immunoperoxidase techniques, in our experience, do not enable differentiation between apocrine and eccrine types of mixed tumors.
- Subjects :
- Adult
Aged
Apocrine Glands analysis
Cell Differentiation
Eccrine Glands analysis
Female
Humans
Immunoenzyme Techniques
Male
Middle Aged
Neoplasms, Germ Cell and Embryonal analysis
Staining and Labeling
Sweat Gland Neoplasms analysis
Apocrine Glands pathology
Eccrine Glands pathology
Neoplasms, Germ Cell and Embryonal pathology
Sweat Gland Neoplasms pathology
Sweat Glands pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0193-1091
- Volume :
- 11
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The American Journal of dermatopathology
- Publication Type :
- Academic Journal
- Accession number :
- 2478041
- Full Text :
- https://doi.org/10.1097/00000372-198910000-00003