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Strain types and antimicrobial resistance patterns of Clostridium difficile isolates from the United States, 2011 to 2013.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2014 Jul; Vol. 58 (7), pp. 4214-8. Date of Electronic Publication: 2014 Apr 21. - Publication Year :
- 2014
-
Abstract
- We determined the PCR ribotypes and antimicrobial susceptibility patterns of 508 toxigenic Clostridium difficile isolates collected between 2011 and 2013 from 32 U.S. hospitals. Of the 29 PCR ribotypes identified, the 027 strain type was the most common (28.1%), although the rates varied by geographic region. Ribotype 014/020 isolates appear to be emerging. Clindamycin and moxifloxacin resistances (36.8% and 35.8%, respectively) were the most frequent resistance phenotypes observed. Reduced susceptibility to vancomycin was observed in 39.1% of 027 isolates.<br /> (Copyright © 2014, American Society for Microbiology. All Rights Reserved.)
- Subjects :
- Clindamycin pharmacology
Clostridioides difficile isolation & purification
Clostridium Infections drug therapy
Clostridium Infections microbiology
Feces microbiology
Fluoroquinolones pharmacology
Humans
Microbial Sensitivity Tests
Moxifloxacin
United States
Vancomycin pharmacology
Vancomycin Resistance
Anti-Bacterial Agents pharmacology
Clostridioides difficile classification
Clostridioides difficile drug effects
Drug Resistance, Multiple, Bacterial genetics
Ribotyping
Subjects
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 58
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 24752264
- Full Text :
- https://doi.org/10.1128/AAC.02775-13