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Epidemiology, diagnosis, and treatment of Hymenoptera venom allergy in mastocytosis patients.
- Source :
-
Immunology and allergy clinics of North America [Immunol Allergy Clin North Am] 2014 May; Vol. 34 (2), pp. 365-81. Date of Electronic Publication: 2014 Mar 15. - Publication Year :
- 2014
-
Abstract
- Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)
- Subjects :
- Allergens immunology
Anaphylaxis diagnosis
Anaphylaxis epidemiology
Anaphylaxis immunology
Animals
Basophil Degranulation Test
Female
Humans
Hymenoptera immunology
Immunoglobulin E blood
Insect Bites and Stings diagnosis
Insect Bites and Stings epidemiology
Insect Bites and Stings immunology
Intradermal Tests
Male
Mastocytosis diagnosis
Mastocytosis epidemiology
Mastocytosis immunology
Anaphylaxis therapy
Arthropod Venoms immunology
Desensitization, Immunologic
Insect Bites and Stings therapy
Mastocytosis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1557-8607
- Volume :
- 34
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Immunology and allergy clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 24745680
- Full Text :
- https://doi.org/10.1016/j.iac.2014.02.004