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Complete Genome Sequences of Eight Helicobacter pylori Strains with Different Virulence Factor Genotypes and Methylation Profiles, Isolated from Patients with Diverse Gastrointestinal Diseases on Okinawa Island, Japan, Determined Using PacBio Single-Molecule Real-Time Technology.
- Source :
-
Genome announcements [Genome Announc] 2014 Apr 17; Vol. 2 (2). Date of Electronic Publication: 2014 Apr 17. - Publication Year :
- 2014
-
Abstract
- We report the complete genome sequences of eight Helicobacter pylori strains isolated from patients with gastrointestinal diseases in Okinawa, Japan. Whole-genome sequencing and DNA methylation detection were performed using the PacBio platform. De novo assembly determined a single, complete contig for each strain. Furthermore, methylation analysis identified virulence factor genotype-dependent motifs.
Details
- Language :
- English
- ISSN :
- 2169-8287
- Volume :
- 2
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Genome announcements
- Publication Type :
- Academic Journal
- Accession number :
- 24744331
- Full Text :
- https://doi.org/10.1128/genomeA.00286-14