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Directed additions of 2-arylpyridines and related substrates to cyclic imines through rhodium-catalyzed C-H functionalization.

Authors :
Parthasarathy K
Azcargorta AR
Cheng Y
Bolm C
Source :
Organic letters [Org Lett] 2014 May 02; Vol. 16 (9), pp. 2538-41. Date of Electronic Publication: 2014 Apr 11.
Publication Year :
2014

Abstract

Rhodium-catalyzed C-H functionalizations have been used for ortho-directed additions of 2-arylpyridines and (hetero)aryl-substituted pyrimidines, isoquinolines, and benzo[h]quinolones to cyclic imines. The resulting amino-functionalized products are formed in good to high yields.

Details

Language :
English
ISSN :
1523-7052
Volume :
16
Issue :
9
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
24720665
Full Text :
https://doi.org/10.1021/ol500918t