Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.

Authors :: Yen PH
Dung DT
Nhiem NX
Anh Hle T
Hang DT
Yen DT
Cuc NT
Ban NK
Van Minh C
Van Kiem P
Source :: Natural product communications [Nat Prod Commun] 2014 Mar; Vol. 9 (3), pp. 383-6.
Publication Year :: 2014
Abstract: Four new cucurbitane-type triterpene glycosides, charantosides D-G (1-4) were isolated from a methanol extract of Momordica charantia fruits. The structures of these compounds were determined by chemical and spectroscopic methods to be (19R)-5 beta,19-epoxy-25-methoxycucurbita-6,23-diene-3 beta,19-diol 3-O-beta-D-glucopyranoside, (19R)-5 beta, 19-epoxy-25-methoxycucurbita-6,23-diene-3 beta,19-diol 3-O-beta-D-allopyranoside, 7 beta-methoxycucurbita-5,23E,25-triene-3 beta-ol 3-O-beta-D-allopyranoside, and 3 beta,7 beta-dihydroxycucurbita-5,23E,25-triene- 19-al 3-O-beta-D-allopyranoside.