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Tfh cell differentiation: missing Stat3 uncovers interferons' interference.

Authors :
Edelmann SL
Heissmeyer V
Source :
Immunity [Immunity] 2014 Mar 20; Vol. 40 (3), pp. 307-9.
Publication Year :
2014

Abstract

Viral infection induces a number of cytokines that shape T cell responses. In this issue of Immunity, Ray et al. (2014) describe how CD4(+) T cells decide on T follicular helper (Tfh) or T helper 1 (Th1) cell skewed gene expression during acute viral infection.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)

Subjects

Subjects :
Animals
Cell Differentiation
Interferon Type I metabolism
STAT3 Transcription Factor metabolism
T-Lymphocytes, Helper-Inducer cytology
T-Lymphocytes, Helper-Inducer metabolism

Details

Language :
English
ISSN :
1097-4180
Volume :
40
Issue :
3
Database :
MEDLINE
Journal :
Immunity
Publication Type :
Academic Journal
Accession number :
24656041
Full Text :
https://doi.org/10.1016/j.immuni.2014.02.008
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