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[Facial angiofibromas associated to tuberous sclerosis treated with topical sirolimus].
- Source :
-
Ugeskrift for laeger [Ugeskr Laeger] 2013 Oct 21; Vol. 175 (43), pp. 2569-70. - Publication Year :
- 2013
-
Abstract
- We present a five-year-old boy with facial angiofibromas associated to tuberous sclerosis successfully treated with topical sirolimus 0.4% applied three times a week for six months. After six months we observed a nearly complete resolution of facial angiofibromas. The blood levels of sirolimus remained under a detectable limit and no side-effects were observed. Topically applied sirolimus seems to be a safe and effective alternative to surgery or laser therapy.
- Subjects :
- Angiofibroma etiology
Angiofibroma pathology
Antibiotics, Antineoplastic administration & dosage
Child, Preschool
Facial Neoplasms etiology
Facial Neoplasms pathology
Humans
Immunosuppressive Agents administration & dosage
Male
Ointments therapeutic use
Sirolimus administration & dosage
Treatment Outcome
Tuberous Sclerosis complications
Angiofibroma drug therapy
Antibiotics, Antineoplastic therapeutic use
Facial Neoplasms drug therapy
Immunosuppressive Agents therapeutic use
Sirolimus therapeutic use
Subjects
Details
- Language :
- Danish
- ISSN :
- 1603-6824
- Volume :
- 175
- Issue :
- 43
- Database :
- MEDLINE
- Journal :
- Ugeskrift for laeger
- Publication Type :
- Academic Journal
- Accession number :
- 24629155