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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry.

Authors :
Regalado EL
Kozlowski MC
Curto JM
Ritter T
Campbell MG
Mazzotti AR
Hamper BC
Spilling CD
Mannino MP
Wan L
Yu JQ
Liu J
Welch CJ
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2014 Apr 14; Vol. 12 (14), pp. 2161-6.
Publication Year :
2014

Abstract

The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.

Details

Language :
English
ISSN :
1477-0539
Volume :
12
Issue :
14
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
24589831
Full Text :
https://doi.org/10.1039/c3ob42195c