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The pre-mRNA splicing reaction.
- Source :
-
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2014; Vol. 1126, pp. 3-12. - Publication Year :
- 2014
-
Abstract
- In eukaryotic organisms, nascent transcripts of protein-coding genes contain intronic sequences that are not present in mature mRNAs. Pre-mRNA splicing removes introns and joins exons to form mature mRNAs. It is catalyzed by a large RNP complex called the spliceosome. Sequences within the pre-mRNA determine intron recognition and excision. This process occurs with a high degree of accuracy to generate the functional transcriptome of a cell.
Details
- Language :
- English
- ISSN :
- 1940-6029
- Volume :
- 1126
- Database :
- MEDLINE
- Journal :
- Methods in molecular biology (Clifton, N.J.)
- Publication Type :
- Academic Journal
- Accession number :
- 24549652
- Full Text :
- https://doi.org/10.1007/978-1-62703-980-2_1