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Injectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate).
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Mar 28; Vol. 50 (25), pp. 3306-9. - Publication Year :
- 2014
-
Abstract
- Injectable PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) have been developed based on complementary hydrazide and aldehyde reactive linear polymer precursors. These hydrogels display the desired biological properties of PEG, form covalent networks in situ following injection, and are easily modulated for improved control over their functionality and physiochemical properties.
- Subjects :
- 3T3 Cells
Adsorption
Animals
Cell Adhesion drug effects
Cell Survival drug effects
Fibrinogen chemistry
Hydrazones chemistry
Hydrogels administration & dosage
Hydrogels pharmacology
Injections, Subcutaneous
Methacrylates administration & dosage
Methacrylates pharmacology
Mice
Mice, Inbred BALB C
Polyethylene Glycols administration & dosage
Polyethylene Glycols pharmacology
Polymethacrylic Acids
Serum Albumin, Bovine chemistry
Hydrogels chemistry
Methacrylates chemistry
Polyethylene Glycols chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 50
- Issue :
- 25
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 24531402
- Full Text :
- https://doi.org/10.1039/c3cc48514e