Back to Search
Start Over
The projective field of retinal bipolar cells and its modulation by visual context.
- Source :
-
Neuron [Neuron] 2014 Feb 05; Vol. 81 (3), pp. 641-52. - Publication Year :
- 2014
-
Abstract
- The receptive field of a sensory neuron spells out all the receptor inputs it receives. To understand a neuron's role in the circuit, one also needs to know its projective field, namely the outputs it sends to all downstream cells. Here we present the projective fields of the primary excitatory neurons in a sensory circuit. We stimulated single bipolar cells of the salamander retina and recorded simultaneously from a population of ganglion cells. Individual bipolar cell signals diverge through polysynaptic pathways into ganglion cells of many different types and over surprisingly large distance. However, the strength and polarity of the projection depend on the cell types involved. Furthermore, visual stimulation strongly modulates the bipolar cell projective field, in opposite direction for different cell types. In this way, the context from distant parts of the visual field can control the routing of signals in the inner retina.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)
- Subjects :
- Action Potentials physiology
Ambystoma
Animals
Cyclooxygenase Inhibitors pharmacology
GABA Antagonists pharmacology
Glycine Agents pharmacology
Larva
Meclofenamic Acid pharmacology
Nerve Net drug effects
Nerve Net physiology
Photic Stimulation
Picrotoxin pharmacology
Retinal Bipolar Cells classification
Retinal Bipolar Cells drug effects
Strychnine pharmacology
Visual Pathways physiology
Models, Neurological
Retina cytology
Retinal Bipolar Cells physiology
Visual Fields physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-4199
- Volume :
- 81
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Neuron
- Publication Type :
- Academic Journal
- Accession number :
- 24507195
- Full Text :
- https://doi.org/10.1016/j.neuron.2013.11.029