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A comparative study of the mini-punch grafting and hair follicle transplantation in the treatment of refractory and stable vitiligo.
- Source :
-
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2014 Apr; Vol. 70 (4), pp. 743-747. Date of Electronic Publication: 2014 Jan 22. - Publication Year :
- 2014
-
Abstract
- Background: Some vitiligo lesions are resistant to all medical treatments.<br />Objective: We sought to compare the efficacy of hair follicle transplantation and mini-punch grafting for the treatment of refractory vitiligo lesions.<br />Methods: A total of 25 patients with stable and resistant vitiligo participated in the study. In each patient, a resistant vitiligo patch was divided into 2 equal parts. One part was treated with hair follicle transplantation and the other part with mini-punch grafting. Postsurgically, the recipient areas were exposed to narrowband ultraviolet B twice a week for 6 months. The diameter of the repigmentation around each graft was measured monthly.<br />Results: At the end of the sixth month, 68% of follicle grafts, and 72% of mini-punch grafts, had repigmentation. The mean diameter of repigmentation around follicle grafts was 5 ± 1.7 mm and around punch grafts was 5.3 ± 1.6 mm. There was no significant difference between the 2 groups statistically (P = .18).<br />Limitations: Small sample size and short time of follow-up are limitations.<br />Conclusions: Because the results of the 2 methods are not statistically different and mini-punch grafting is much easier to do than follicular transplantation, we recommend mini-punch grafting to treat drug-resistant vitiligo.<br /> (Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.)
- Subjects :
- Adult
Biopsy, Needle
Female
Graft Rejection
Graft Survival
Humans
Iran
Male
Middle Aged
Prognosis
Prospective Studies
Risk Assessment
Severity of Illness Index
Treatment Outcome
Vitiligo diagnosis
Young Adult
Hair Follicle transplantation
Skin Pigmentation physiology
Skin Transplantation methods
Vitiligo surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6787
- Volume :
- 70
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of the American Academy of Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 24461995
- Full Text :
- https://doi.org/10.1016/j.jaad.2013.11.044