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[New alternatives for the treatment of antiphospholipid syndrome. A literature review].
- Source :
-
Revista medica de Chile [Rev Med Chil] 2013 Aug; Vol. 141 (8), pp. 1041-8. - Publication Year :
- 2013
-
Abstract
- For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different levels, the cascade of events leading to the pro-thrombotic state characteristic of the antiphospholipid syndrome. We conducted a literature review of these new treatments, focusing on the pathophysiological bases that support them and their possible clinical applications.
- Subjects :
- Agmatine analogs & derivatives
Agmatine therapeutic use
Antibodies, Monoclonal, Murine-Derived therapeutic use
Antiphospholipid Syndrome physiopathology
Dipeptides therapeutic use
Glucocorticoids therapeutic use
Humans
Hydroxychloroquine therapeutic use
Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Rituximab
Thrombosis drug therapy
Antiphospholipid Syndrome drug therapy
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0717-6163
- Volume :
- 141
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Revista medica de Chile
- Publication Type :
- Academic Journal
- Accession number :
- 24448861
- Full Text :
- https://doi.org/10.4067/S0034-98872013000800011