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[Current view on gut microbiota].
- Source :
-
Annales pharmaceutiques francaises [Ann Pharm Fr] 2014 Jan; Vol. 72 (1), pp. 15-21. Date of Electronic Publication: 2013 Oct 16. - Publication Year :
- 2014
-
Abstract
- Gut microbiota is more and more important since metagenomic research have brought new knowledge on this topic especially for human health. Firstly, gut microbiota is a key element for our organism he lives in symbiosis with. Secondly, it interacts favorably with many physiological functions of our organism. Thirdly, at the opposite, it can be an active participant in intestinal pathologies linked to a dysbiosis mainly in chronic inflammatory bowel diseases like Crohn disease or ulcerative colitis but also in obesity, metabolic syndrome, and more prudently in autism and behavioral disorders. In order to keep a good health, it is essential to protect our gut microbiota as soon as our young age and maintain it healthy. Face to a more and more important number of publications for treating certain digestive diseases with fecal microbial transplantation, it needs to be very careful and recommend further studies in order to assess risks and define standardized protocols. Gut microbiota metabolic capacities towards xenobiotics need to be developed, and we must take an interest in the modifications they induce on medicinal molecules. On the other hand, it is essential to study the potent effects of pesticides and other pollutants on microbiota functions.<br /> (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Animals
Bacterial Translocation
Complementary Therapies
Environmental Pollutants pharmacokinetics
Feces microbiology
Humans
Inflammation microbiology
Inflammation therapy
Intestines embryology
Intestines growth & development
Mammals microbiology
Probiotics therapeutic use
Symbiosis
Xenobiotics pharmacokinetics
Intestines microbiology
Microbiota
Subjects
Details
- Language :
- French
- ISSN :
- 0003-4509
- Volume :
- 72
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annales pharmaceutiques francaises
- Publication Type :
- Academic Journal
- Accession number :
- 24438664
- Full Text :
- https://doi.org/10.1016/j.pharma.2013.09.001