Back to Search
Start Over
Fit4Life: a weight loss intervention for children who have survived childhood leukemia.
- Source :
-
Pediatric blood & cancer [Pediatr Blood Cancer] 2014 May; Vol. 61 (5), pp. 894-900. Date of Electronic Publication: 2014 Jan 16. - Publication Year :
- 2014
-
Abstract
- Background: Children surviving acute lymphoblastic leukemia (ALL) are at increased risk for overweight and obesity over that of the general population. Whether a generic or tailored approach to weight management is needed for cancer survivors has yet to be tested.<br />Procedure: Thirty-eight youth 8-18 years with BMI ≥ 85% who had survived ALL were recruited for a randomized clinical trial evaluating a weight management intervention (WMI) tailored for childhood ALL survivors (Fit4Life). Fit4Life recipients received a 4-month web, phone, and text message-delivered WMI tailored for cancer survivorship. Controls received a general WMI delivered via phone and mail. Assessments were performed at baseline and 4 months. Outcome data were analyzed according to assigned treatment condition over time.<br />Results: Most (80%, (70%, 100%) [median (IQR)]) of the assigned curriculum was received by Fit4Life participants as compared to 50% (40%, 65%) among controls. Fit4Life recipients ≥ 14 years demonstrated less weight gain (P = 0.05) and increased moderate-to-vigorous physical activity (P < 0.01) while all Fit4Life recipients reported reduced negative mood (P < 0.05) over time as compared to control counterparts.<br />Conclusions: We demonstrated acceptable feasibility of a WMI tailored for overweight and obese children surviving ALL utilizing a multimodal technology approach. Improved weight, weight-related behavior, and psychological outcomes were demonstrated among Fit4Life intervention as compared to youth receiving a generic WMI. Data from this pilot trial may be used to design a larger trial to determine whether youth of all ages also can derive a benefit from a cancer survivor-tailored WMI and whether short-term outcomes translate into improved long-term outcomes for childhood ALL survivors.<br /> (© 2014 Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Body Mass Index
Case-Control Studies
Child
Female
Follow-Up Studies
Health Behavior
Health Promotion
Humans
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma psychology
Prognosis
Risk Reduction Behavior
Exercise Therapy
Obesity therapy
Overweight therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma rehabilitation
Survivors psychology
Weight Loss
Subjects
Details
- Language :
- English
- ISSN :
- 1545-5017
- Volume :
- 61
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pediatric blood & cancer
- Publication Type :
- Academic Journal
- Accession number :
- 24436138
- Full Text :
- https://doi.org/10.1002/pbc.24937