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[Long-term survival of a case with advanced sigmoid colon cancer and Virchow's lymph node metastasis].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2013 Nov; Vol. 40 (12), pp. 2083-5. - Publication Year :
- 2013
-
Abstract
- A 63-year-old man presented with a tumor in his left supraclavicular fossa. Aspiration biopsy of the tumor revealed metastasis of an adenocarcinoma. Further examination indicated the presence of advanced sigmoid colon cancer with metastases to Virchow's lymph nodes and the para-aortic lymph nodes. Sigmoidectomy with D3 lymph node dissection was performed. Histological examination revealed moderately and well differentiated adenocarcinomas( double cancers) that had invaded the subserosa as well as metastases of the para-aortic lymph nodes. Twelve days after the operation, systemic chemotherapy with FOLFOX4 (8 courses), followed by FOLFIRI (8 courses) was administered. Six months later, CT examination determined that the metastases of Virchow's lymph nodes and the para-aortic lymph nodes had completely disappeared. Capecitabine was administered for approximately 1 year, and complete response was achieved. However, a pancreatic tumor measuring 2×3 cm was detected 44 months after the operation. Distal pancreatectomy was performed and pathological examination that included immunohistochemical staining (CK7 and CK20) of the tumor indicated the primary pancreatic cancer. The patient was treated with chemoradiotherapy after the operation and survived for 5 years and 9 months after the initial operation.
- Subjects :
- Adenocarcinoma drug therapy
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Humans
Lymphatic Metastasis
Male
Middle Aged
Pancreatic Neoplasms drug therapy
Prognosis
Sigmoid Neoplasms drug therapy
Time Factors
Adenocarcinoma secondary
Adenocarcinoma surgery
Pancreatic Neoplasms secondary
Pancreatic Neoplasms surgery
Sigmoid Neoplasms pathology
Sigmoid Neoplasms surgery
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 40
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 24394020