Back to Search
Start Over
Myasthenia gravis: predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan.
- Source :
-
Journal of neuroimmunology [J Neuroimmunol] 2014 Feb 15; Vol. 267 (1-2), pp. 97-101. Date of Electronic Publication: 2013 Dec 22. - Publication Year :
- 2014
-
Abstract
- For a brief period, an increased incidence of elevated anti-acetylcholine receptor antibody titer was observed in patients with myasthenia gravis (MG) in Kanazawa, Japan. The purpose of this study was to examine the predictive factors associated with this antibody titer elevation. Decreased odds of titer elevation were seen in patients with early-onset MG than in those with late-onset MG. In patients with non-thymoma-related MG, thymectomy prevented the antibody titer elevation. Our data suggest that late-onset MG may have a different immunogenic response and the thymus might play an immunoregulatory role against extrinsic factors in some types of MG.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Subjects :
- Adult
Age of Onset
Aged
Female
Follow-Up Studies
Humans
Japan epidemiology
Male
Middle Aged
Myasthenia Gravis surgery
Predictive Value of Tests
Thymectomy
Thymoma immunology
Thymoma metabolism
Thymoma surgery
Antibodies metabolism
Myasthenia Gravis immunology
Myasthenia Gravis metabolism
Receptors, Cholinergic immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1872-8421
- Volume :
- 267
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Journal of neuroimmunology
- Publication Type :
- Academic Journal
- Accession number :
- 24388223
- Full Text :
- https://doi.org/10.1016/j.jneuroim.2013.12.011