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Study protocol of a randomized controlled trial comparing Mindfulness-Based Stress Reduction with treatment as usual in reducing psychological distress in patients with lung cancer and their partners: the MILON study.
- Source :
-
BMC cancer [BMC Cancer] 2014 Jan 03; Vol. 14, pp. 3. Date of Electronic Publication: 2014 Jan 03. - Publication Year :
- 2014
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Abstract
- Background: Lung cancer is the leading cause of cancer death worldwide and characterized by a poor prognosis. It has a major impact on the psychological wellbeing of patients and their partners. Recently, it has been shown that Mindfulness-Based Stress Reduction (MBSR) is effective in reducing anxiety and depressive symptoms in cancer patients. The generalization of these results is limited since most participants were female patients with breast cancer. Moreover, only one study examined the effectiveness of MBSR in partners of cancer patients. Therefore, in the present trial we study the effectiveness of MBSR versus treatment as usual (TAU) in patients with lung cancer and their partners.<br />Methods/design: A parallel group, randomized controlled trial is conducted to compare MBSR with TAU. Lung cancer patients who have received or are still under treatment, and their partners are recruited. Assessments will take place at baseline, post intervention and at three-month follow-up. The primary outcome is psychological distress (i.e. anxiety and depressive symptoms). Secondary outcomes are quality of life (only for patients), caregiver appraisal (only for partners), relationship quality and spirituality. In addition, cost-effectiveness ratio (only in patients) and several process variables are assessed.<br />Discussion: This trial will provide information about the clinical and cost-effectiveness of MBSR compared to TAU in patients with lung cancer and their partners.
- Subjects :
- Anxiety economics
Anxiety etiology
Anxiety psychology
Clinical Protocols
Cost-Benefit Analysis
Depression economics
Depression etiology
Depression psychology
Female
Health Care Costs
Humans
Interpersonal Relations
Lung Neoplasms complications
Lung Neoplasms economics
Lung Neoplasms therapy
Male
Netherlands
Psychiatric Status Rating Scales
Quality of Life
Spirituality
Stress, Psychological economics
Stress, Psychological etiology
Stress, Psychological psychology
Surveys and Questionnaires
Time Factors
Treatment Outcome
Anxiety prevention & control
Depression prevention & control
Lung Neoplasms psychology
Mindfulness economics
Patients psychology
Research Design
Spouses psychology
Stress, Psychological prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2407
- Volume :
- 14
- Database :
- MEDLINE
- Journal :
- BMC cancer
- Publication Type :
- Academic Journal
- Accession number :
- 24386906
- Full Text :
- https://doi.org/10.1186/1471-2407-14-3