Back to Search Start Over

Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients.

Authors :
Sahin F
Saydam G
Cömert M
Uz B
Yavuz AS
Turan E
Yönal I
Atay H
Keltikli E
Turgut M
Pehlivan M
Akay MO
Gürkan E
Paydaş S
Kahraman S
Demirkan F
Kırkızlar O
Akpınar S
Pamuk GE
Demir M
Ozbaş HM
Sönmez M
Gültürk M
Salihoğlu A
Eşkazan AE
Ar C
Haydaroğlu Şahin H
Ongören S
Başlar Z
Aydın Y
Yenere MN
Tüzüner N
Ferhanoğlu B
Haznedaroglu IC
Ilhan O
Soysal T
Source :
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2013 Dec; Vol. 30 (4), pp. 351-8. Date of Electronic Publication: 2013 Dec 05.
Publication Year :
2013

Abstract

Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices.<br />Materials and Methods: In this article, we have evaluated 1133 patients' results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs.<br />Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment.<br />Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care.<br />Conflict of Interest: None declared.

Details

Language :
English
ISSN :
1300-7777
Volume :
30
Issue :
4
Database :
MEDLINE
Journal :
Turkish journal of haematology : official journal of Turkish Society of Haematology
Publication Type :
Academic Journal
Accession number :
24385824
Full Text :
https://doi.org/10.4274/tjh.2013.0151