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Hypoglycemic activity of Ficus racemosa bark in combination with oral hypoglycemic drug in diabetic human.
- Source :
-
Acta poloniae pharmaceutica [Acta Pol Pharm] 2013 Nov-Dec; Vol. 70 (6), pp. 1045-9. - Publication Year :
- 2013
-
Abstract
- Medicinal herbs, used in indigenous medicines in crude forms for the management of diabetes mellitus, contain both the organic and inorganic constituents. The aim of the study was to find out the hypoglycemic effect of Ficus racemosa in a group of diabetic subjects taking oral hypoglycemic drug. Twenty five of each, male and female, diabetic patients, selected from Fatima Jinnah Medical College, Lahore, Pakistan, taking oral hypoglycemic drug were included in this study and were given orally the extract (5 mL) of bark of Ficus racemosa (about 100 mg) two times for 15 days. Blood samples for estimation of blood glucose and parameters of liver and renal functions were estimated. It was observed that after taking the herb in combination with drug, blood glucose level (fasting and after breakfast) was markedly decreased in both male and female but significant difference was only observed in sugar level of males after 1.5 h after breakfast. To rule out herb toxicity, liver and renal functions tests of patients was also performed which were observed to be in normal range. Present investigation established a pharmacological evidence to support the folklore claim that Ficus racemosa is good anti-diabetic agent.
- Subjects :
- Administration, Oral
Blood Glucose metabolism
Diabetes Mellitus blood
Drug Therapy, Combination
Female
Humans
Hypoglycemic Agents adverse effects
Hypoglycemic Agents isolation & purification
Male
Middle Aged
Pakistan
Phytotherapy
Plant Bark
Plant Extracts adverse effects
Plant Extracts isolation & purification
Plants, Medicinal
Time Factors
Treatment Outcome
Blood Glucose drug effects
Diabetes Mellitus drug therapy
Ficus chemistry
Hypoglycemic Agents administration & dosage
Plant Extracts administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 0001-6837
- Volume :
- 70
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Acta poloniae pharmaceutica
- Publication Type :
- Academic Journal
- Accession number :
- 24383328