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Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru.
- Source :
-
Journal of clinical microbiology [J Clin Microbiol] 2014 Mar; Vol. 52 (3), pp. 968-70. Date of Electronic Publication: 2013 Dec 26. - Publication Year :
- 2014
-
Abstract
- Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).
- Subjects :
- Adolescent
Adult
Animals
Blood microbiology
Child
Child, Preschool
DNA Gyrase genetics
Female
Genotype
Humans
Male
Microbial Sensitivity Tests
Mutation, Missense
Peru
Salmonella typhi isolation & purification
Young Adult
Anti-Bacterial Agents pharmacology
Ciprofloxacin pharmacology
Drug Resistance, Bacterial
Salmonella typhi drug effects
Typhoid Fever microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1098-660X
- Volume :
- 52
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of clinical microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 24371234
- Full Text :
- https://doi.org/10.1128/JCM.02663-13