Effect of silane coupling agent treated bovine bone based carbonated hydroxyapatite on in vitro degradation behavior and bioactivity of PLA composites.

Authors :: Rakmae S
Ruksakulpiwat Y
Sutapun W
Suppakarn N
Source :: Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2012 Aug 01; Vol. 32 (6), pp. 1428-36. Date of Electronic Publication: 2012 Apr 23.
Publication Year :: 2012
Abstract: In this study, effect of treating bovine bone based carbonated hydroxyapatite (CHA) with silane coupling agent on in vitro degradation and bioactivity of PLA composites were investigated. PLA composite specimens containing CHA and silane-treated CHA were immersed in phosphate-buffered solution at 37 °C for the periods of time up to 8 weeks. The changes in specimen weights and morphologies, pH of PBS solution and PLA molecular weight were examined. The results showed that the strong interfacial bonding between silane-treated CHA and PLA matrix significantly delayed in vitro degradation of the PLA composites. However, the bioactivity of the PLA/silane treated CHA composites, determined by the formation of poorly crystalline calcium phosphate compounds on the specimen surface after immersion in simulated body fluid (SBF), seemed to be lower than that of the PLA/CHA composite.<br /> (Copyright © 2012 Elsevier B.V. All rights reserved.)

Subjects :: Animals
Body Fluids chemistry
Calcium Compounds chemistry
Cattle
Phosphates chemistry
Polyesters
Powders chemistry
Bone and Bones chemistry
Durapatite chemistry
Lactic Acid chemistry
Polymers chemistry
Silanes chemistry

Language :: English
ISSN :: 1873-0191
Volume :: 32
Issue :: 6
Database :: MEDLINE
Journal :: Materials science & engineering. C, Materials for biological applications
Publication Type :: Academic Journal
Accession number :: 24364942
Full Text :: https://doi.org/10.1016/j.msec.2012.04.022

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