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Common stress and serum cortisol and IL-12 levels in missed abortion.
- Source :
-
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [J Obstet Gynaecol] 2014 Jan; Vol. 34 (1), pp. 33-5. - Publication Year :
- 2014
-
Abstract
- To investigate stress levels, serum cortisol levels, and changes in IL-12 concentration in patients with missed abortion. Patients with missed abortion (n = 48) were age and gestational age-matched with normal early pregnancy cases (n = 48). All subjects completed a stress evaluation survey questionnaire about common stressors. Venous blood samples were collected at 07.00 hours, and serum cortisol and IL-12 concentrations were measured by electrochemiluminescence immunoassay and ELISA methods, respectively. Missed abortion patients demonstrated a significantly higher number of common stressors and higher serum cortisol levels compared to controls (both p < 0.05). Dilation and curettage did not lead to significant differences in serum cortisol and IL-12 levels (p > 0.05). Stress and immunity alterations of the immune system may contribute to the aetiology of missed abortion.
Details
- Language :
- English
- ISSN :
- 1364-6893
- Volume :
- 34
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 24359046
- Full Text :
- https://doi.org/10.3109/01443615.2013.830089