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Two new isoflavone glycosides from the vine stem of Millettia dielsiana.

Authors :
Gong T
Zhang T
Wang DX
Chen RY
Liu P
Yu DQ
Source :
Journal of Asian natural products research [J Asian Nat Prod Res] 2014; Vol. 16 (2), pp. 181-6. Date of Electronic Publication: 2013 Dec 11.
Publication Year :
2014

Abstract

Two new isoflavone glycosides, millesianins F (1) and G (2), along with 11 known ones (3-13) have been isolated from the n-butanol extract of the vine stems of Millettia dielsiana Harms. The structures of 1 and 2 were established as cladrastin 7-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (1) and fujikinetin 7-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (2) by means of spectroscopic analysis and chemical methods. Some isolates (compounds 1, 3, 4, 5, 6, and 11) were tested for their effects on the proliferation of hematopoietic progenitor cell, and the preliminary results showed that all of investigated compounds had moderate activities but not in dose-dependent manners.

Details

Language :
English
ISSN :
1477-2213
Volume :
16
Issue :
2
Database :
MEDLINE
Journal :
Journal of Asian natural products research
Publication Type :
Academic Journal
Accession number :
24325313
Full Text :
https://doi.org/10.1080/10286020.2013.860967