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Two new isoflavone glycosides from the vine stem of Millettia dielsiana.
- Source :
-
Journal of Asian natural products research [J Asian Nat Prod Res] 2014; Vol. 16 (2), pp. 181-6. Date of Electronic Publication: 2013 Dec 11. - Publication Year :
- 2014
-
Abstract
- Two new isoflavone glycosides, millesianins F (1) and G (2), along with 11 known ones (3-13) have been isolated from the n-butanol extract of the vine stems of Millettia dielsiana Harms. The structures of 1 and 2 were established as cladrastin 7-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (1) and fujikinetin 7-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (2) by means of spectroscopic analysis and chemical methods. Some isolates (compounds 1, 3, 4, 5, 6, and 11) were tested for their effects on the proliferation of hematopoietic progenitor cell, and the preliminary results showed that all of investigated compounds had moderate activities but not in dose-dependent manners.
- Subjects :
- Dose-Response Relationship, Drug
Drugs, Chinese Herbal chemistry
Drugs, Chinese Herbal pharmacology
Glycosides chemistry
Glycosides pharmacology
Hematopoietic Stem Cells
Isoflavones chemistry
Isoflavones pharmacology
Molecular Structure
Plant Stems chemistry
Drugs, Chinese Herbal isolation & purification
Glycosides isolation & purification
Isoflavones isolation & purification
Millettia chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1477-2213
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of Asian natural products research
- Publication Type :
- Academic Journal
- Accession number :
- 24325313
- Full Text :
- https://doi.org/10.1080/10286020.2013.860967