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Cancer-associated myositis: a 35-year retrospective study of a monocentric cohort.
- Source :
-
Rheumatology international [Rheumatol Int] 2014 Apr; Vol. 34 (4), pp. 565-9. Date of Electronic Publication: 2013 Dec 10. - Publication Year :
- 2014
-
Abstract
- This study is aimed at retrospectively studying cancer-associated inflammatory myopathies (CAM) in a cohort of patients with inflammatory myopathies. CAM were diagnosed if the tumor was diagnosed 2 years before or after disease onset. One hundred and sixty-two patients were included, 27 (17 %) had CAM. A significant association was observed between CAM and dermatomyositis (DM), older age and dysphagia at disease onset. CAM have lower creatine kinase (CK) levels at onset and a low prevalence of autoantibodies. In conclusion, the association of male sex, older age, DM, dysphagia at onset, lower CK, and autoantibodies negativity carries a high suspicion of CAM.
- Subjects :
- Age Factors
Autoantibodies blood
Biomarkers blood
Creatine Kinase blood
Deglutition Disorders epidemiology
Dermatomyositis epidemiology
Female
Humans
Italy epidemiology
Kaplan-Meier Estimate
Male
Middle Aged
Myositis blood
Myositis diagnosis
Myositis mortality
Myositis therapy
Neoplasms diagnosis
Neoplasms mortality
Neoplasms therapy
Predictive Value of Tests
Prevalence
Prognosis
Retrospective Studies
Risk Factors
Time Factors
Myositis epidemiology
Neoplasms epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1437-160X
- Volume :
- 34
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Rheumatology international
- Publication Type :
- Academic Journal
- Accession number :
- 24322453
- Full Text :
- https://doi.org/10.1007/s00296-013-2910-1