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Cancer-associated myositis: a 35-year retrospective study of a monocentric cohort.

Authors :
Neri R
Barsotti S
Iacopetti V
Iacopetti G
Pepe P
d'Ascanio A
Tavoni AG
Mosca M
Bombardieri S
Source :
Rheumatology international [Rheumatol Int] 2014 Apr; Vol. 34 (4), pp. 565-9. Date of Electronic Publication: 2013 Dec 10.
Publication Year :
2014

Abstract

This study is aimed at retrospectively studying cancer-associated inflammatory myopathies (CAM) in a cohort of patients with inflammatory myopathies. CAM were diagnosed if the tumor was diagnosed 2 years before or after disease onset. One hundred and sixty-two patients were included, 27 (17 %) had CAM. A significant association was observed between CAM and dermatomyositis (DM), older age and dysphagia at disease onset. CAM have lower creatine kinase (CK) levels at onset and a low prevalence of autoantibodies. In conclusion, the association of male sex, older age, DM, dysphagia at onset, lower CK, and autoantibodies negativity carries a high suspicion of CAM.

Details

Language :
English
ISSN :
1437-160X
Volume :
34
Issue :
4
Database :
MEDLINE
Journal :
Rheumatology international
Publication Type :
Academic Journal
Accession number :
24322453
Full Text :
https://doi.org/10.1007/s00296-013-2910-1