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Inducing cellular aging: enabling neurodegeneration-in-a-dish.

Authors :
Brennand KJ
Source :
Cell stem cell [Cell Stem Cell] 2013 Dec 05; Vol. 13 (6), pp. 635-6.
Publication Year :
2013

Abstract

The immaturity of neurons differentiated from human induced pluripotent stem cells (hiPSCs) presents difficulties for modeling late-onset neurodegenerative disorders such as Parkinson's disease. Now, Miller et al. (2013) provide a strategy for inducing aging-related phenotypes in hiPSC-derived neurons, enabling in vitro study of late-onset neurodegenerative diseases.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1875-9777
Volume :
13
Issue :
6
Database :
MEDLINE
Journal :
Cell stem cell
Publication Type :
Academic Journal
Accession number :
24315433
Full Text :
https://doi.org/10.1016/j.stem.2013.11.017