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[Amyotrophic lateral sclerosis in totally locked-in state].
- Source :
-
Rinsho shinkeigaku = Clinical neurology [Rinsho Shinkeigaku] 2013; Vol. 53 (11), pp. 1399-401. - Publication Year :
- 2013
-
Abstract
- Seven autopsy patients with amyotrophic lateral sclerosis (ALS) in totally locked-in state (TLS) were examined neuropathologically. The patients were composed of 4 males and 3 females, and 3 with familial, 1 sporadic but with mutation in SOD1 gene, and 3 sporadic patients with unremarkable gene mutation. The brains weighed 715, 783, 1,019, 1,050, 1,170, 1,190 or 1,233 g. The tegmentum of the brain stem was markedly degenerated in every patient, and the tracts relating to the somatic sensory and auditory were involved in the lesions.
- Subjects :
- Adult
Aged
Amyotrophic Lateral Sclerosis physiopathology
Amyotrophic Lateral Sclerosis psychology
Brain pathology
Brain physiopathology
Female
Humans
Male
Middle Aged
Motor Neurons pathology
Amyotrophic Lateral Sclerosis pathology
Amyotrophic Lateral Sclerosis rehabilitation
Brain-Computer Interfaces
Communication
Communication Aids for Disabled
Subjects
Details
- Language :
- Japanese
- ISSN :
- 1882-0654
- Volume :
- 53
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Rinsho shinkeigaku = Clinical neurology
- Publication Type :
- Academic Journal
- Accession number :
- 24292003
- Full Text :
- https://doi.org/10.5692/clinicalneurol.53.1399