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A bicyclic diterpenoid with a new 15,16-dinorlabdane carbon skeleton from Leonurus japonicus and its coagulant bioactivity.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2013 Nov 11; Vol. 18 (11), pp. 13904-9. Date of Electronic Publication: 2013 Nov 11. - Publication Year :
- 2013
-
Abstract
- A new 15,16-dinorlabdane diterpenoid 1 and a known labdane diterpenoid 2, together with three known ergosterols 3-5, were isolated from the EtOAc-soluble portion of the EtOH extract of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. Compound 1 showed in vitro coagulant activity in the APTT, PT, TT, and FIB assays.
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 18
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 24284488
- Full Text :
- https://doi.org/10.3390/molecules181113904