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Radiocontrast-induced thyroid dysfunction: is it common and what should we do about it?
- Source :
-
Clinical endocrinology [Clin Endocrinol (Oxf)] 2014 Mar; Vol. 80 (3), pp. 322-7. Date of Electronic Publication: 2013 Dec 17. - Publication Year :
- 2014
-
Abstract
- There has been a substantial increase in the use of radiocontrast-enhanced imaging studies in the past two decades (particularly computed tomography and coronary angiography). Sudden exposure to high levels of iodide may result in thyroid dysfunction (hyperthyroidism and hypothyroidism alike). Although the adverse-event rate is not very high, the condition is notable considering the large number of contrast-enhanced radiographic studies performed. Clinicians often have to decide on the most suitable diagnostic modality and the safest contrast medium when it comes to certain patients. In this study, we stress that the thyroid function of the patients should also be taken into consideration while making such decisions. We discuss in detail the prevalence and types (hypothyroidism and hyperthyroidism) of radiocontrast-induced thyroid dysfunction. We list the subsets of the population that are at a higher risk of radiocontrast-induced thyroid dysfunction and summarize the necessary prophylaxis and possible treatment. The presented principles apply to intravenous, intra-arterial and enteral (endoscopic retrograde cholangiopancreatography) routes of iodinated contrast medium administration.<br /> (© 2013 John Wiley & Sons Ltd.)
- Subjects :
- Adolescent
Adult
Child
Child, Preschool
Diagnostic Imaging adverse effects
Female
Humans
Infant
Iodine administration & dosage
Iodine toxicity
Iodine Radioisotopes administration & dosage
Iodine Radioisotopes adverse effects
Iodine Radioisotopes toxicity
Maximum Tolerated Dose
Pregnancy
Thyroid Diseases prevention & control
Contrast Media adverse effects
Iodine adverse effects
Thyroid Diseases chemically induced
Thyroid Diseases epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1365-2265
- Volume :
- 80
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- 24283715
- Full Text :
- https://doi.org/10.1111/cen.12376