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Radial versus femoral approach comparison in percutaneous coronary intervention with intraaortic balloon pump support: the RADIAL PUMP UP registry.
- Source :
-
American heart journal [Am Heart J] 2013 Dec; Vol. 166 (6), pp. 1019-26. Date of Electronic Publication: 2013 Oct 10. - Publication Year :
- 2013
-
Abstract
- Background: The role of intraaortic balloon pump (IABP) during percutaneous coronary intervention (PCI) in high-risk acute patients remains debated. Device-related complications and the more complex patient management could explain such lack of clinical benefit. We aimed to assess the impact of transradial versus transfemoral access for PCI requiring IABP support on vascular complications and clinical outcome.<br />Methods: We retrospectively analyzed 321 consecutive patients receiving IABP support during transfemoral (n = 209) or transradial (n = 112) PCI. Thirty-day net adverse clinical events (NACEs) (composite of postprocedural bleeding, cardiac death, myocardial infarction, target lesion revascularization, and stroke) were the primary end point, with access-related bleeding and hospital stay as secondary end points.<br />Results: Cardiogenic shock and hemodynamic instability were the most common indications for IABP support. Cumulative 30-day NACE rate was 50.2%, whereas an access site-related bleeding occurred in 14.3%. Patients undergoing transfemoral PCI had a higher unadjusted rate of NACEs when compared with the transradial group (57.4% vs 36.6%, P < .01), mainly due more access-related bleedings (18.7% vs 6.3%, P < .01). Such increased risk of NACEs was confirmed after propensity score adjustment (hazard ratio 0.57 [0.4-0.9], P = .007), whereas hospital stay appeared comparable in the 2 groups.<br />Conclusions: In this observational registry, high-risk patients undergoing PCI and requiring IABP support appeared to have fewer NACEs if transradial access was used instead of transfemoral, mainly due to fewer access-related bleedings. Given the inherent limitations of this retrospective work, including the inability to adjust for unknown confounders, further controlled studies are warranted to confirm or refute these findings.<br /> (© 2013.)
- Subjects :
- Aged
Aged, 80 and over
Female
Humans
Intra-Aortic Balloon Pumping adverse effects
Male
Middle Aged
Percutaneous Coronary Intervention adverse effects
Retrospective Studies
Treatment Outcome
Acute Coronary Syndrome therapy
Femoral Artery
Intra-Aortic Balloon Pumping methods
Myocardial Infarction therapy
Percutaneous Coronary Intervention methods
Radial Artery
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6744
- Volume :
- 166
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- American heart journal
- Publication Type :
- Academic Journal
- Accession number :
- 24268216
- Full Text :
- https://doi.org/10.1016/j.ahj.2013.09.009