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The effects of subfascial wound versus epidural levo-bupivacaine infusion on postoperative pain following hysterectomy.
- Source :
-
Minerva anestesiologica [Minerva Anestesiol] 2014 Jul; Vol. 80 (7), pp. 769-78. Date of Electronic Publication: 2013 Nov 21. - Publication Year :
- 2014
-
Abstract
- Background: Local analgesia through wound catheters is used as a part of multimodal analgesia. The efficacy of continuous subfascial wound infusion compared to epidural analgesia is unknown for abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) via Pfannenstiel incision. The aim of this study was to compare the aforementioned two methods in this type of surgery for postoperative morphine consumption, acute and persistent postsurgical pain.<br />Methods: Fifty patients enrolled in the study were randomly allocated to receive continuous 10 mL/h levobupivacaine either via subfascial (Group S) or epidural (Group E) catheter for 48 h postoperatively. In Group S 0.25% levobupivacaine was used for the first six hours and 0.125% thereafter, whereas Group E received 0.125% levobupivacaine throughout the study period. Cumulative morphine consumption, static and dynamic pain, gastrointestinal recovery, ambulation, patient satisfaction, hospital stay, as well as pain at 2nd and 6th months were evaluated.<br />Results: Group S was superior to Group E regarding cumulative morphine consumption (16.8±7.2 mg and 28.7±10.3 mg respectively, P<0.001; mean difference -11.9 with 95% CI of the difference -17.1 to -6.7) and pain relief. Patient satisfaction was higher in Group S compared to Group E (P=0.006). Less postoperative vomiting was observed in Group S. No difference was detected in length of hospital stay and persistent postsurgical pain incidence.<br />Conclusion: Wound analgesia via subfascial catheter with continuous levobupivacaine infusion decreases postoperative morphine consumption and increases patient satisfaction compared to epidural analgesia with no difference in persistent postsurgical pain following TAH-BSO via Pfannenstiel incision.
- Subjects :
- Analgesics, Opioid administration & dosage
Analgesics, Opioid therapeutic use
Anesthesia, Epidural
Bupivacaine administration & dosage
Bupivacaine therapeutic use
Female
Humans
Levobupivacaine
Middle Aged
Morphine administration & dosage
Morphine therapeutic use
Anesthetics, Local administration & dosage
Anesthetics, Local therapeutic use
Bupivacaine analogs & derivatives
Hysterectomy adverse effects
Pain, Postoperative drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1827-1596
- Volume :
- 80
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Minerva anestesiologica
- Publication Type :
- Academic Journal
- Accession number :
- 24257146