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Characterisation of a type 1 Avian Paramyxovirus belonging to a divergent group.
- Source :
-
Veterinary microbiology [Vet Microbiol] 2014 Jan 10; Vol. 168 (1), pp. 25-33. Date of Electronic Publication: 2013 Oct 24. - Publication Year :
- 2014
-
Abstract
- Newcastle disease, induced by a type 1 Avian Paramyxovirus (APMV-1), is one of the most serious poultry diseases. APMV-1 are divided into two classes based on genetic analysis: class II strains have been recovered from wild or domestic birds and include virulent and avirulent isolates whereas class I strains have been mainly isolated from wild birds and are avirulent. Within class I, a new proposed genotype has recently been reported. The only full genome strain of this group is presently characterised from the point of view of codon usage with reference to class I and class II specificities. Class-specific residues were identified on HN and F proteins that are the two major proteins involved in cell attachment and pathogenicity. Comparison of protein patterns and codon usage for this newly identified APMV-1 strain indicates it is similar to class I viruses but contains a few characteristics close to the viruses of class II. Transmission of viruses from this recently identified divergent group from wild birds to domestic birds could have a major impact on the domestic poultry industry.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Subjects :
- Animals
Animals, Wild virology
Birds
Codon genetics
Genotype
HN Protein genetics
Newcastle Disease transmission
Newcastle disease virus isolation & purification
Newcastle disease virus pathogenicity
Phylogeny
Poultry
Poultry Diseases transmission
Viral Fusion Proteins genetics
Newcastle Disease virology
Newcastle disease virus classification
Newcastle disease virus genetics
Poultry Diseases virology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2542
- Volume :
- 168
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Veterinary microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 24238668
- Full Text :
- https://doi.org/10.1016/j.vetmic.2013.10.005