A traceless directing group for C-H borylation.

Authors :: Preshlock SM
Plattner DL
Maligres PE
Krska SW
Maleczka RE Jr
Smith MR 3rd
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2013 Dec 02; Vol. 52 (49), pp. 12915-9. Date of Electronic Publication: 2013 Nov 12.
Publication Year :: 2013
Abstract: Not a trace: Borylation of the nitrogen in nitrogen heterocycles or anilines provides a traceless directing group for subsequent catalytic C-H borylation. Selectivities that previously required Boc protection can be achieved; furthermore, the NBpin directing group can be installed and removed in-situ, and product yields are substantially higher. Boc=tert-butoxycarbonyl, pin=pinacolato.<br /> (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)