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Antioxidant neolignans from Cordia americana.

Authors :
Fernández LR
Cirigliano A
Fabani MP
Lima B
Alberti S
Kramer F
Tapia AA
Cabrera G
Palermo JA
Sánchez M
Source :
Planta medica [Planta Med] 2013 Dec; Vol. 79 (18), pp. 1724-9. Date of Electronic Publication: 2013 Nov 12.
Publication Year :
2013

Abstract

Five new neolignans with a bicyclo[2.2.2]octene framework were isolated from an ethanolic extract of the bark of Cordia americana. The structures and relative configurations of the compounds were elucidated by a combination of spectroscopic methods. All the isolated compounds showed good antioxidant activities in the DPPH radical scavenging (0.5-100 µg/mL) and Ferric-reducing antioxidant power (FRAP, 1-100 µg/mL) assays. One of the compounds displayed mild fungistatic activity at 0.1 µmol/spot against Fusarium virguliforme while, at the same time, all compounds were inactive against several strains of Gram (+) and Gram (-) bacteria at all assayed concentrations (10-1,000 µg/mL).<br /> (Georg Thieme Verlag KG Stuttgart · New York.)

Details

Language :
English
ISSN :
1439-0221
Volume :
79
Issue :
18
Database :
MEDLINE
Journal :
Planta medica
Publication Type :
Academic Journal
Accession number :
24222042
Full Text :
https://doi.org/10.1055/s-0033-1351052