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Antioxidant neolignans from Cordia americana.
- Source :
-
Planta medica [Planta Med] 2013 Dec; Vol. 79 (18), pp. 1724-9. Date of Electronic Publication: 2013 Nov 12. - Publication Year :
- 2013
-
Abstract
- Five new neolignans with a bicyclo[2.2.2]octene framework were isolated from an ethanolic extract of the bark of Cordia americana. The structures and relative configurations of the compounds were elucidated by a combination of spectroscopic methods. All the isolated compounds showed good antioxidant activities in the DPPH radical scavenging (0.5-100 µg/mL) and Ferric-reducing antioxidant power (FRAP, 1-100 µg/mL) assays. One of the compounds displayed mild fungistatic activity at 0.1 µmol/spot against Fusarium virguliforme while, at the same time, all compounds were inactive against several strains of Gram (+) and Gram (-) bacteria at all assayed concentrations (10-1,000 µg/mL).<br /> (Georg Thieme Verlag KG Stuttgart · New York.)
- Subjects :
- Antifungal Agents chemistry
Antifungal Agents pharmacology
Antioxidants chemistry
Antioxidants pharmacology
Bacteria drug effects
Bridged Bicyclo Compounds
Free Radical Scavengers chemistry
Free Radical Scavengers isolation & purification
Free Radical Scavengers pharmacology
Fusarium drug effects
Lignans chemistry
Lignans pharmacology
Medicine, Traditional
Molecular Structure
Oxidation-Reduction
Plant Bark chemistry
Plant Extracts chemistry
Plant Extracts isolation & purification
Plant Extracts pharmacology
Plants, Medicinal
Antifungal Agents isolation & purification
Antioxidants isolation & purification
Cordia chemistry
Lignans isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1439-0221
- Volume :
- 79
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- Planta medica
- Publication Type :
- Academic Journal
- Accession number :
- 24222042
- Full Text :
- https://doi.org/10.1055/s-0033-1351052