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Enhancement in anti-Semliki Forest virus activity of ds RNA by a muramyl dipeptide.
- Source :
-
FEBS letters [FEBS Lett] 1986 May 05; Vol. 200 (1), pp. 37-41. - Publication Year :
- 1986
-
Abstract
- Antiviral activity of an interferon-inducing mycoviral ds RNA against Semliki Forest virus infection was considerably enhanced by N-palmitoylmuramyl-L-alanyl-D-isoglutamine (PMDP), a new muramyl dipeptide. This enhancement in activity was not due to increased production of interferon, but resulted probably from a PMDP-induced increase in nonspecific resistance to infection. These results indicate that a combined treatment with an interferon inducer and muramyl dipeptide may prove highly useful to control effectively viral infections.
Details
- Language :
- English
- ISSN :
- 0014-5793
- Volume :
- 200
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- FEBS letters
- Publication Type :
- Academic Journal
- Accession number :
- 2422061
- Full Text :
- https://doi.org/10.1016/0014-5793(86)80506-3