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Nanopore-based sequencing and detection of nucleic acids.
- Source :
-
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2013 Dec 09; Vol. 52 (50), pp. 13154-61. Date of Electronic Publication: 2013 Nov 08. - Publication Year :
- 2013
-
Abstract
- Nanopore-based techniques, which mimic the functions of natural ion channels, have attracted increasing attention as unique methods for single-molecule detection. The technology allows the real-time, selective, high-throughput analysis of nucleic acids through both biological and solid-state nanopores. In this Minireview, the background and latest progress in nanopore-based sequencing and detection of nucleic acids are summarized, and light is shed on a novel platform for nanopore-based detection.<br /> (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Subjects :
- Base Sequence
Models, Molecular
Nanotechnology
Nanopores
Nucleic Acids analysis
Subjects
Details
- Language :
- English
- ISSN :
- 1521-3773
- Volume :
- 52
- Issue :
- 50
- Database :
- MEDLINE
- Journal :
- Angewandte Chemie (International ed. in English)
- Publication Type :
- Academic Journal
- Accession number :
- 24214738
- Full Text :
- https://doi.org/10.1002/anie.201303529