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Tandem duplications in the C-terminal domain of the mesotocin receptor exclusively identified among East Eurasian thrushes.
- Source :
-
Journal of molecular evolution [J Mol Evol] 2013 Dec; Vol. 77 (5-6), pp. 260-7. Date of Electronic Publication: 2013 Nov 06. - Publication Year :
- 2013
-
Abstract
- Mesotocin is a neurohypophyseal hormone found in some non-mammalian vertebrates, including birds, reptiles, and amphibians. In this study, we identified and characterized 18-amino acid duplications in the C-terminal domain of the mesotocin receptor (MTR), specifically found in Turdus thrushes (Aves: Passeriforms: Turdidae). These duplicated elements are located in the distal part of the C-terminal tails of MTR and consist of amino acids that are highly conserved among major vertebrates. Intraspecific polymorphisms in a variable number of tandem duplications are commonly found in East Eurasian Turdus, but not in any other genus of Turdidae. Moreover, the genus Turdus can be further classified into 2 groups according to the presence or absence of a 3-amino acid deletion just adjacent to the putative palmitoylation site in the cytoplasmic C-terminal tail. The phylogeny presented here strongly supports the conspecific group of 4 East Eurasian thrushes (Turdus pallidus, T. chrysolaus, T. obscurus, and T. celaenops). Our findings, therefore, provide a new synapomorphy that can be used for phylogenetic assumptions and shed a light on the history of diversification within Eurasian Turdus clades.
- Subjects :
- Amino Acid Sequence
Animals
Base Sequence
DNA Primers genetics
Genotype
Molecular Sequence Data
Polymerase Chain Reaction
Sequence Alignment
Sequence Analysis, DNA
Sex Determination Analysis
Species Specificity
Passeriformes genetics
Phylogeny
Polymorphism, Genetic genetics
Receptors, Pituitary Hormone genetics
Tandem Repeat Sequences genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1432
- Volume :
- 77
- Issue :
- 5-6
- Database :
- MEDLINE
- Journal :
- Journal of molecular evolution
- Publication Type :
- Academic Journal
- Accession number :
- 24193891
- Full Text :
- https://doi.org/10.1007/s00239-013-9590-z