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[Differential diagnosis for detection of hyphae in tissue].
- Source :
-
Der Pathologe [Pathologe] 2013 Nov; Vol. 34 (6), pp. 503-10. - Publication Year :
- 2013
-
Abstract
- Usually the detection of hyphae in tissue is unmistakable evidence of a deep mycosis requiring antimycotic treatment. Micromorphology alone rarely allows a specific diagnosis, thus confusion is possible between Candida, Aspergillus, Alternaria and Fusarium species or several other fungal agents. If broad, nearly non-septated hyphae are detected histologically mucormycosis can be suspected. Detection of hyphae in tissue is always a cause for concern because therapeutic consequences must follow. Because therapeutic strategies may differ depending on the specific fungal agent, a suspected diagnosis should be supplemented by other methods, e.g. culture of unfixed specimens, by immunohistology or molecular biological methods.
- Subjects :
- Antifungal Agents therapeutic use
Aspergillosis pathology
Diagnosis, Differential
Fungi classification
Fungi drug effects
Fungi isolation & purification
Fusariosis drug therapy
Fusariosis microbiology
Fusariosis pathology
Humans
Hyalohyphomycosis pathology
Mycological Typing Techniques
Mycoses drug therapy
Mycoses microbiology
Phaeohyphomycosis pathology
Prognosis
Scedosporium classification
Scedosporium drug effects
Scedosporium isolation & purification
Hyphae ultrastructure
Mycoses pathology
Subjects
Details
- Language :
- German
- ISSN :
- 1432-1963
- Volume :
- 34
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Der Pathologe
- Publication Type :
- Academic Journal
- Accession number :
- 24154751
- Full Text :
- https://doi.org/10.1007/s00292-013-1829-3