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On-chip processing of particles and cells via multilaminar flow streams.
- Source :
-
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2014 Jan; Vol. 406 (1), pp. 139-61. Date of Electronic Publication: 2013 Oct 23. - Publication Year :
- 2014
-
Abstract
- The processing of particles, cells, and droplets for reactions, analyses, labeling, and coating is an important aspect of many microfluidic workflows. However, performing multi-step processes is typically a laborious and time-consuming endeavor. By exploiting the laminar nature of flow within microchannels, such procedures can benefit in terms of both speed and simplicity. This can be achieved either by manipulating the flow streams around the objects of interest, particularly for the localized perfusion of cells, or by manipulating the objects themselves within the streams via a range of forces. Here, we review the variety of methods that have been employed for performing such "multilaminar flow" procedures on particles, cells, and droplets.
- Subjects :
- Animals
Arabidopsis cytology
Arabidopsis physiology
Cell Adhesion
Diffusion
Eukaryotic Cells cytology
Eukaryotic Cells physiology
Humans
Magnetic Fields
Microfluidics instrumentation
Optical Tweezers
Particle Size
Biomechanical Phenomena physiology
Microfluidic Analytical Techniques
Microfluidics methods
Rheology methods
Subjects
Details
- Language :
- English
- ISSN :
- 1618-2650
- Volume :
- 406
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Analytical and bioanalytical chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 24150283
- Full Text :
- https://doi.org/10.1007/s00216-013-7363-6