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Urinary dysfunction with detrusor hyperactivity in women with Parkinson's disease cannot be blamed as a factor of worsening motor performance.
- Source :
-
Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2013 Sep; Vol. 71 (9A), pp. 591-5. - Publication Year :
- 2013
-
Abstract
- Introduction: Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature.<br />Methods: A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated.<br />Results: Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups.<br />Conclusion: Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.
- Subjects :
- Aged
Aged, 80 and over
Cohort Studies
Disease Progression
Female
Humans
Middle Aged
Parkinson Disease physiopathology
Prognosis
Prospective Studies
Severity of Illness Index
Parkinson Disease complications
Psychomotor Performance
Urinary Bladder, Overactive complications
Urination Disorders etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1678-4227
- Volume :
- 71
- Issue :
- 9A
- Database :
- MEDLINE
- Journal :
- Arquivos de neuro-psiquiatria
- Publication Type :
- Academic Journal
- Accession number :
- 24141437
- Full Text :
- https://doi.org/10.1590/0004-282X20130101