Membrane depolarization-induced RhoA/Rho-associated kinase activation and sustained contraction of rat caudal arterial smooth muscle involves genistein-sensitive tyrosine phosphorylation.

Subjects

Subjects :

Amides pharmacology
Animals
Calcium metabolism
Calcium physiology
In Vitro Techniques
Male
Myosin-Light-Chain Phosphatase metabolism
Phosphorylation drug effects
Potassium physiology
Protein Phosphatase 1 metabolism
Protein Tyrosine Phosphatases antagonists & inhibitors
Protein-Tyrosine Kinases antagonists & inhibitors
Pyridines pharmacology
Rats
Rats, Sprague-Dawley
Vanadates pharmacology
rho-Associated Kinases antagonists & inhibitors
rho-Associated Kinases metabolism
Arteries drug effects
Genistein pharmacology
Membrane Potentials physiology
Muscle Contraction drug effects
Muscle, Smooth, Vascular drug effects
Protein Kinase Inhibitors pharmacology
Protein-Tyrosine Kinases metabolism
Tyrosine metabolism
rho-Associated Kinases physiology

Details

Language :

English

ISSN :

1884-8796

Volume :

49

Database :

MEDLINE

Journal :

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi

Publication Type :

Academic Journal

Accession number :

24133693

Full Text :

https://doi.org/10.1540/jsmr.49.26