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Interarytenoid botulinum toxin injection for recalcitrant vocal process granuloma.
- Source :
-
The Laryngoscope [Laryngoscope] 2013 Dec; Vol. 123 (12), pp. 3084-7. Date of Electronic Publication: 2013 Sep 20. - Publication Year :
- 2013
-
Abstract
- Objectives/hypothesis: This study evaluated the efficacy of botulinum toxin type A injected into the interarytenoid muscle to treat recalcitrant vocal process granulomas.<br />Study Design: Retrospective clinical review at a tertiary care center.<br />Methods: Eight patients with vocal process granulomas refractory to a variety of prior treatments including surgical resection, proton pump inhibitor therapy, and voice therapy underwent percutaneous injection of botulinum toxin type A into the interarytenoid muscle, performed in an office setting. Doses ranged from 5 U to 25 U in one to two injections.<br />Results: One patient demonstrated no improvement, two patients demonstrated partial resolution, and five patients demonstrated complete resolution of their granulomas. Four patients noted transient breathiness. There were no other side effects. All patients tolerated the injections without difficulty.<br />Conclusion: Botulinum toxin injection into the interarytenoid muscle appears to be a safe and effective modality for treating recalcitrant vocal process granuloma.<br /> (Copyright © 2013 The American Laryngological, Rhinological and Otological Society, Inc.)
- Subjects :
- Dose-Response Relationship, Drug
Electromyography
Granuloma, Laryngeal diagnosis
Granuloma, Laryngeal physiopathology
Humans
Injections, Intramuscular
Laryngeal Muscles
Laryngoscopy
Retrospective Studies
Treatment Outcome
Botulinum Toxins, Type A administration & dosage
Granuloma, Laryngeal drug therapy
Vocal Cords drug effects
Voice Quality drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1531-4995
- Volume :
- 123
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Laryngoscope
- Publication Type :
- Academic Journal
- Accession number :
- 24115127
- Full Text :
- https://doi.org/10.1002/lary.23915